Medical Team experiments in microgravity conditions
The project aims to study the behaviour of ABC transporters (biological agents responsible for the elimination of drugs and other toxins from human cells) under microgravity conditions. To achieve these conditions, the experiment was carried out using a succession of ESA parabolic flights.
Once in weightless conditions, experiments are carried out to evaluate the activity of the family of ABC transporters. During the last years, we have been developing an action protocol that will allow us to accurately measure the activity of the ABC transporter during parabolic flights.
An experiment is carried out under normal gravity conditions in order to compare whether gravitational forces are capable of affecting the activity of the transporter. In order to understand in more detail the mechanism of action of transporters, inhibitors capable of regulating transporter function will be used.